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DEFINITION: (noun) A small, flat, pigmented spot on the skin. SYNONYMS: freckle. USAGE: The dermatologist advised the patient to keep an eye on the large lentigo near her lip and to alert him if there was a change in its size or shape.

It has long been believed that centuries of erosion destroyed the land bridge between France and Britain, but a new study suggests that a single, catastrophic event was likely the cause. Scientists using high-resolution sonar data now claim that 400,000 years ago, in one of the largest floods on Earth, the land bridge connecting the two masses was broken apart. A 2nd "megaflood," occurring more than 160,000 years ago, deepened the gap and created the characteristic valley system found in the English Channel.

Alzheimer's is a degenerative disease of nerve cells in the cerebral cortex that leads to atrophy of the brain and senile dementia. First described in 1906, the disease is characterized by abnormal accumulation of plaques and malformed nerve cells. The disease usually affects people over age 65; short-term memory loss is an early symptom. The cause of Alzheimer's is not known, and, as yet, there is no known cure. How do chess and crossword puzzles factor into Alzheimer's prevention?